Yes, Backblaze B2 Cloud Storage will work with Linux. In fact, we expect a significant percentage of our customers to use B2 from Linux.
B2 is fully compatible with Linux.
Our B2 Command Line Tool runs on Linux. You can learn more about it here: https://www.backblaze.com/b2/docs/quick_command_line.html.
Projects and products that run on Linux are introducing B2 support. A list can be found on our integration page.